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We apply this method to compare continentally diverse populations, as well as Northern and Southern Europeans. Another approach to identifying signals of selection through population comparison is the cross-population extended haplotype heterozygosity test (XP-EHH), which was designed to detect ongoing or nearly fixed selective sweeps by comparing haplotypes from two populations. However, a limitation is that unlike the single-population CLR method, this method does not model the joint allele frequency spectrum under selection, and thus cannot support a likelihood ratio test.